Primary lateral sclerosis (PLS) is a very rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles.PLS belongs to a group of disorders known as motor neuron diseases.Motor neuron diseases develop when the nerve cells that control voluntary muscle movement degenerate and die, causing weakness in the muscles they control. Pls. Med Question. Close. 8. Posted by 1 day ago. Pls. Med Question. I’m staying the night far away from home and just realized I didn’t bring my night lithium dose, pls reassure me that I’ll be ok missing one dose. I take 2 doses a day. Thx I’m very anxious about this. 8 comments. share. save. hide. Showing posts with label PLS. Show all posts. Showing posts with label PLS. Show all posts. 26 September 2021. So I was Thinking. by R.T. Lawton. So, anyway, I was thinking that maybe I should expand my field of writing and possibly try some new markets. I could always write some horror short stories and see how that went, but to enter that ... PLS Is Here For You! Because You Deserve Better ®. Our products and services can vary by state, based on local laws and regulations. Please select your state to get the most accurate information about the products and services we offer near you. PLS Inc, a Petroleum Listing Service, provides the Oil & Gas industry with News Reports, Assets for Sale, PLS Dealmakers Expo, M&A database & PLS docFinder. clean everything before bed, pls. ty! 淪 ♀️ DOP Sonasereirith Katam 0 Followers, 3 Following, 0 Posts - See Instagram photos and videos from Aris Liu (@pls_memoree) pls like and komen kalau korang aku buat apa lepas ni PLS’ website is a great tool and easy to use for in depth research and tracking as well as for a quick inquiry. Often in lobbying, things change quickly and I love having the ability to rely on PLS from my iphone to confirm new and/or updated information." Kathleen Duffy Bruder. Saxton & Stump Central Library Development Aid Library System Pop. (2010 Census) 2020-2021 Approp Ed Law Ed Law w/HH Approp. Central Book Aid Approp. Ed Law Ed Law w/HH
2021.09.28 06:13 Icy_Uchiha Data transfer?? pls halp
Hello all. ok, so i used to play a while ago on a chromebook. I had a bad phone and couldn't run it. I now have a better phone and can run it. I tried going back to my chromebook to transfer the data to my phone. Turns out, saoif is no longer compatible with chromebook. I can't open the app because of an old version or whatever. Is my account lost forever???? i hope not :/. but ya, pls help.
submitted by Icy_Uchiha to IntegralFactor [link] [comments]
2021.09.28 06:13 pen15es Do ultimate edition owners get a free ones to watch?
2021.09.28 06:13 JHRP307 I guess this is it. What an amazing game
2021.09.28 06:13 xdhpv Local hyperthermia combined with topical imiquimod cleared extensive and recalcitrant common warts on the scalp [case study]
From the paper:
A 37-year-old man complained of dozens of gray or skincolored papules on his scalp for 6 years. Six years ago, he noticed two gray papules about 2-to-3 mm in diameter on his scalp. Since then, the number and sizes of the papules increased gradually. He was diagnosed with viral warts in his local hospital and was treated with CO2 ablative laser about 10 times. Some of the warty lesions cleared while leaving atrophic scars over the treated area. However, there was continuing growth of old lesions and appearance of new ones on his head; several flat papules also developed on his right thigh, four years ago. Three years ago, he was treated with topical imiquimod (on the head lesions) combined with subcutaneous injection of BCG-polysaccharide nucleic acid (twice a week) for 3 months, but to no avail. His past history was generally good.
Physical examination revealed dozens of papules ranging from approximately 1-to-6 mm in diameter, with a slight hyperkeratotic and rough surface (figures 1A,B). There were five flat grayish or skin-colored papules on his right thigh ranging from 1-to-3 mm in diameter. We identified human papillomavirus 57 (HPV-57) by PCR method from the scrapes on the target papule on his scalp before giving hyperthermia treatment.
We initiated local hyperthermia on the largest wart on his scalp as the target lesion [1,2]. Briefly, we applied local hyperthermia on the target lesion at a surface temperature of 44 ◦C for 30 minutes on days 1, 2, 3, 17 and 18. We observed no noticeable changes during a 6 month follow-up. Then we applied topical 5% imiquimod cream (Zhuhai United Laboratories Co., Ltd.) on the target lesion, every other day for 20 days. Immediately after the application of topical imiquimod, we repeated another round of local hyperthermia treatment. A month after completion of the treatment, both targeted and untargeted warts on his scalp became reddish, the patient felt obvious itching lasting for four days, then all the warty lesions on his scalp disappeared completely in a week without any residual changes. Even the hair in the warty lesions appeared normal (figures 1C,D). One of the lesions on his thigh cleared, while the other ones remained unchanged. The patient declined further treatment for the lesions on his thigh as he regarded them trivial matters. There was no sign of recurrence on his scalp and the lesions on his thigh remained unchanged during a 6-month follow-up. By PCR assay, we detected HPV 2, 3 from the scrapes of the remaining lesion on his thigh. (...)
Local hyperthermia could induce a significant increase in the transcriptional expression of interferon (IFN)-alfa, IFN-beta and IFN-gamma, in a temperature-dependent manner in condyloma acuminata , could promote migration and maturation of LCs , and induce abundant infiltrating CD4+ T and CD8+ T lymphocytes, as well as macrophages and CD1a+ dendritic cells in the regressing warts . Imiquimod, a TLR7,8 agonist, induces pro-inflammatory cytokines, chemokines and other mediators, leading to activation of antigen-presenting cells and other components of innate immunity and, eventually, the mounting of a profound T-helper (Th1)-weighted cellular immune response. The combination of the two may be synergistic, mounting a robust anti-HPV response .
The full study (PDF):
submitted by xdhpv to HPV [link] [comments]
2021.09.28 06:13 AtmosphereSuperb2263 https://t.me/joinchat/7CMOc8kXzH80MTM0
2021.09.28 06:13 AltWolfy0913 You know I was reallyyy bored and I wanted listen some music but gacha at same time and this happened (plz tell if someone already posted something like this)
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2021.09.28 06:13 Trans-on-trans Check out my baby boy!
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2021.09.28 06:13 prawnbiryani 💗☁🍦🌸🧁🤍🦩
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2021.09.28 06:13 MGY4011990 “Perhaps we sort too soon”
2021.09.28 06:13 OliverMarkusMalloy Covid-denier and Antivaxx dumbfuck caught Covid. Oops! Now he's all mad and went on a bat shit crazy tirade, cursing out the left: "fUcK yOuR mOtHeRs dEeP aNd hArD!"
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2021.09.28 06:13 wonsis I’m getting lucky
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2021.09.28 06:13 d-n-y- Las Vegas: The Last Outpost of Western Civilization (1996)
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2021.09.28 06:13 The_Normies_Must_Pay Anyone else?
I found a stratagy that actually works. Backstory, I have really bad luck when i go to war with my neighbors. Either they're fleetpower is too much, they are technological gods, or they have an ally is didn't know about; and i always end up dead.
I found out a good way to fight a defensive after provoking an enemy. I always kit out starbases on the only hyperlanes that lead into my empire and move all fleets to defend them; to form a defensive shield that keeps enemies from invading into friendly space. Coupled with mods like Gigastructural Engineering, and i can use astroid artillery to further defend until the enemy has exhausted their fleets and i can bombard their planets. Anyone else have a similar stratagy?
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2021.09.28 06:13 HelloEgo LF: Darumaka FT: HA Magikarp or any (SH Exclusive)
2021.09.28 06:13 BiCelebLVR Anyone else think JLO is the hottest she’s ever been now?
2021.09.28 06:13 alexo2802 Good luck to all the first hours players :)
I’m EST timezone, can’t make it for either the 2am release or 8am release as I work 9-6. I hope the release will be great and there won’t be too many technical issues, my prayers have been sent ～(つˆ0ˆ)つ｡☆
See you all in game in.. 18 hours from now :p
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2021.09.28 06:13 Overson_YT xMRxGR33Nx, I have no clue when we became friends, but we are super close to being best friends, and I just want to say that it's been an honor
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2021.09.28 06:13 Upstairs_Loquat_1535 Colors live just arrived today
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2021.09.28 06:13 romain34230 French Days : Amazon n’a pas fini, voici 10 pépites pour ce mardi
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2021.09.28 06:13 Yelo_it Quieres morbosear a esta putita? Te dejo un regalo en los comentarios 👇👇🔥🔥
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2021.09.28 06:13 uGoTaCHaNCe Ontario Rent Control Rules
I can't seem to find an exact answer anywhere to this question but I was curious to know if anyone has an understanding of the November 15, 2018 rule regarding rent control exemptions.
Here is a link to the rent increase rules:
The guideline applies to most residential rental accommodations covered by the Residential Tenancies Act. It does not apply to rental units in buildings occupied for the first time after November 15, 2018, social housing units, long-term care homes or commercial property.
This excerpt above is what I am referring to. I own a condo that I lived in as my primary residence from 2010 to 2020 before buying a second property which became my new primary residence. Does this count as not being a rental unit until after the date?
I have tried contacting the LTB and have gotten some conflicting advice. Curious to know how others perceive this rule? Am I exempt or is my unit rent controlled?
submitted by uGoTaCHaNCe to legaladvicecanada [link] [comments]
2021.09.28 06:13 Spiritfeed___ Looking for a CKII event: “Sometimes I think I died on that field and this all has been a bad dream, sometimes I cannot breathe”
2021.09.28 06:13 Snipercake2 The answer to titles, the universe, and everything: 42
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2021.09.28 06:13 StrfshQueen Seen on a bag of gluten free flour from Italy - love the care and attention that Italians pay when it comes to making sure something is truly gluten free!
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2021.09.28 06:13 beepit5671 Im not defending michaela or zack but this dynamic has become cringe
Seriously seeing this woman full of life,admittingly with issues,turned into a stepford "yes zack" :|,expressionlesd back patter
Really is disturbing
Anyone else agree
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